Combined impact of drug-drug interaction and cirrhosis
Definitions
AUCuCIR* / AUCuCIR
This ratio is useful for adapting the dose of the substrate in a cirrhotic patient in whom an optimal dose had been found but an interacting drug is added to the current treatment.
AUCuCIR* / AUCu
This ratio is useful for adapting the initial dose of the substrate to be given to a cirrhotic patient in whom the interacting drug is already prescribed.